We are serial renovators, very little puts us off. We can see through dirt, disorder and plain bad taste.
The exception, we helped DS buy his first flat, needed renovating and was very good value, but the previous occupant was a chain smoker and everything in the house was ingrained with tarry residues.
We are non-smokers and just assumed a good scrub and several coats of paint would sort it out. It didn't, we had to repaint some of the walls every year as the tar oozed through. I would now never consider a house that had been occupied by a smoker.
Anything else we can deal with if the house is what we are looking for, where we want it