I took Prednisolone for Vasculitis (an autoimmune condition), earlier this year. I had a course of 13 weeks. 10 a day for 4 weeks, then reduced by 1 a week for the remaining weeks.
I'd never felt so strange - after 3 weeks, I had the typical steroid "moon face*, then shakiness, a feeling of being detached from reality (spaced-out), huge increase in appetite, puffy fingers and feet, nausea, and just about every side-effect there is. The Neurologist told me I had to take them and finish the course, which I did. When I saw him recently, he apologised for the way the tablets had affected me, and agreed that I'll never willingly take them again.