It's an interesting subject overthehill.
NHS advice is not to take ibuprofen if you have a history of a strong, unpleasant reaction (hypersensitivity) to aspirin or other non-steroid anti-inflammatory drugs. Patients with IBD are advised not to take ibuprofen. It can cause ulcers in your stomach or gut.
In conversation with an anaesthetist about post-operative pain relief, his advice was not to take ibuprofen but to use paracetomol.
In other words, both aspirin and ibuprofen are bad for the gut.
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