I think Catherine has an inflammatory bowel/intestinal condition that may contribute to her her being thin. She originally went into hospital for an undisclosed major abdominal surgery - it was an unexpected consequence of that surgery that the cancer was detected but we never found out the reason for the original surgery.
Catherine has always been very sporty and has always done a lot of engagements that involved putting her sports kit on and engaging in physical activity - rugby, hiking, abseiling, hockey, tennis. So she does not appear to be "thin and weak"
Her mother and sister are also very slim so a large part seems to be genetics.
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