It is a very complex issue and I find myself quite challenged by it. On the one hand, I feel it is a good thing that there is screening for things like Downs, cystic fibrosis, etc., to enable parents to decide whether they wish to, or feel equipped to, deal with the challenges involved. I can see, though, those who decide not to screen or to go ahead with pregnancies that indicate conditions such as Downs can so easily be labelled as "irresponsible". That is what I find worrying.
It is difficult to know at what point our interference with nature becomes undesirable or damaging. Many of the things we do could be interpreted as "meddling" but most people agree with surgical and drug interventions instead of just letting nature take its course.
My understanding is that intelligence is thought by many neuroscientists to be largely heritable but that extremely intelligent people do not continue to produce children who are even more intelligent than themselves. I believe there is what is called a "return to the mean" - so that at some point super-intelligent people start to produce less intelligent children until they return to a point of average intelligence. (I may be wrong - I think I read something like this when I was studying psychology but that was some time ago and things might have moved on since then). And there have been many examples of parents with average IQs producing children who are described as "geniuses".
I would be very concerned about screening for traits such as, "criminality", alcoholism, "employment resistance", etc. - and I can't understand how Perkins from King's College can estimate the figure of 94,040 "extra" people having been "created by the welfare state" due to a rise in welfare spending. Also how is criminal behaviour defined? I happen to think that some very undesirable behaviour - greed, lying for one's own benefit, etc. - would not necessarily be seen as "criminal" whereas stealing to feed one's own or others' children would be.
Isn't there a danger of creating a conveyer belt of characterless human beings - a bit like those people who have extensive plastic surgery and end up with the same bland, slightly wierd appearances? I think that creativity, innovation and discovery in the arts and sciences is often driven by intellectual, emotional and physical challenges and that it is also an important part of being human to accept difference and to behave with compassion. To "iron out" all the differences between people would lead to a sort of blank mediocrity. We might then just as well be robots.